This Nationally Determined Contribution communicates the government of the United States' economy-wide target of reducing its net greenhouse gas emissions by 61-66 percent below 2005 levels in 2035. The Contribution specifies United States' efforts to address climate change through research, education, training, and workforce development, creation of high quality jobs, climate-focused workforce development and education, and investments that benefit disadvantaged communities. Concerning emissions reduction in various sectors, this Contribution focuses on the following, through targeted and specific measures: accelerating clean energy transition and deployment; protecting public health; development of carbon capture technologies to cut pollution from existing power plants; improving public-private partnership to remove clean energy deployment barrier; strengthening climate-smart agriculture, forestry, and land management practices; improving practices as reforestation, grazing management, nutrient management, agroforestry, and wetland restoration; reducing wildfire and increasing public incentives to capture methane from agriculture facilities; cutting pollution in building sector towards zero emissions target; strengthening clean transportation services; spurring industrial transformation to reduce industrial emissions.